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THE CARDIOVASCULAR SYSTEM

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The Cardiovascular system is part of the circulatory system that circulates blood. The circulatory system also includes the lymphatic system, which circulates lymph, but the terms circulatory system and Cardiovascular system are commonly used interchangeably to describe blood circulation. The Cardiovascular system consists of the heart, blood, and vessels. it Has 2 sides, each of which has 2 Chambers. 

The best- known function of the circulatory system is perhaps the transport of inhaled oxygen from the lungs to body's tissues, and removal of carbon dioxide in the opposite direction to be exhaled. Basically, oxygen-Poor blood from the body Returns to right side of the heart, where it is pumpen to the lungs.

In The lungs, Blood picks up Oxygen and Release carbon dioxide. Oxygen- rich blood then Returns to the left side of the heart. This part of the system is called the purmonary circuit.  Th left side of the heart pumps oxygen-rich blood to body's tissues, where it unloads oxygen and picks up carbon dioxide. The Resulting deoxyenated. Blood again Returns to the heart's right side to complete the cycle.  This part iss the systemic circuit.

because the heart's left side has to pump blood to the entire body, it has much thicker muscle than the right side. There are 4 valves which Serve to ensure one-way blood flow through the heart: oxygen-Poor moves from left atrium to left ventricle to the aorta. The heart is enclosed in adouble - walled protective sac called the pericardium. The pericardial cavity contains a fluid which Serves as lubricant and allows the heart to  contract and relax with Minimum Friction.

The heart wall has 3 layers

the outer layer, epicardium, lines the pericardial cavity, the inner layer, endocardium, lines heart 
Chambers and valves and is continuous with the endothelium of blood vessels, and the thick middle layer,  myocardium, is the muscle tissue responsible for the beating of the heart.  The contraction of the heart muscles is initiated by electrical impulses, known as action potentials. unlike skeletal muscles, which have to be stimulated by the nervous system, the heart  generates its own electrical stimulation.
The impulses start from a small group of cells called the pacemaker cells, which constitute the cardiac conduction system. 

The primary pacemaker is the SA node, it initiatives all heartbeats and controls heart rate. Apart from transporting gases. The blood also supplies body's tissues with nutrients and removes metabolic wastes. Wastes are then filtered  from the blood in the kidneys and removed. In urine. The blood also carries hormones from endocrine glands to target, organs, and plays an important role in the body's immune defense.

The blood has two main components

 a clear extracellular fluid called plasma, and the so-called formed elements which include red blood cells, white blood cells and platelets.  Red blood cells transport oxygen and carbon dioxide;  white blood cells participate in various defense mechanisms against invading organisms; while the platelets are responsible for blood clotting, minimising blood loss during an injury.

The blood circulatory system is a closed loop, meaning the blood itself never leaves the vessels. Instead, substances diffuse through the walls, of blood vessels to vessels to move to and from the surrounding tissues. Vessels that move blood away from from the heart are called arteries, while that bring blood back to the heart are veins. 
arteries usually carry  oxygenated blood while veins carry deoxygenated blood. For pulmonary arteries and veins, however, the reverse is true.

The  usual route of blood flow is

 heart to Large arteries, smaller arteries, then even smaller arteries,called arterioles, then smallest blood vessels called capillaries, where the exchange of substances takes place. Blood then collects into small veins, called venules, then to larger veins and back to the heart. Arteries and veins essentially Serve to conduct blood, their walls consist of 3 layers: A middle layer of mostly smooth muscles allows the vessels to constrict or dilate, regulating.
-and an inner layer consisted of thin squamous endothelium, separated from outer layers by a basement Membrane. In General, larger vessels have more connective tissue and smooth muscle. 

In addition, arteries have more muscles than veins because they carry blood away from the heart and must withstand higher pressure generated by the beating of the heart. The walls of capillaries, whose function is to exchange substances between the blood and surrounding tissue, consist solely of a thin endothelium with its basement Membrane, thus permitting easy diffusion of blood solutes.


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